Welcome to the HBR video brief. I’m Todd Pruzan, Senior Research and Special Projects Editor at the Harvard Business Review. Today I’m here with Jonathan Schaf, CIO of Parexel, one of the world’s largest clinical research organizations. Jonathan has over 30 years of IT experience and joined Parexel in November 2022 to lead the development of innovative technologies and solutions to meet customer needs in an ever evolving and growing clinical trial environment.
Jonathan is here to talk about the importance of digital transformation and its impact on the research industry, as well as the impact of modernized technologies on clinical trial patients. Jonathan, thank you so much for being with us today.
Jonathan: Thank you very much for inviting me. I am very happy to be here and I appreciate that you asked me to do so.
TP: Thank you, Jonathan. What is a Clinical Research Organization (CRO) and how has technology changed the industry?
DS: That’s a great question. First of all, CRO is a contract research organization that provides clinical trials and research services primarily to pharmaceutical and biotech companies, and sometimes to non-pharmaceutical and non-biotech companies. CROs typically test the safety and efficacy of new drugs, vaccines, and other medical procedures, such as medical devices, before they are made available to patients. So this process includes early clinical research, also known as prehuman research, and what we like to call first human research.
The CRO industry is relatively young – it started in the 1980s. Although there were tools such as Microsoft Excel, some databases, and of course pen and paper, for many years there were not many technologies that supported clinical research. But if you look back from 2010 to 2011, there’s a whole industry that has coalesced around contract research and pharmaceutical research and development in general, and it’s really expanded around the world.
TP: So what does digital transformation look like at Parexel? What are you trying to achieve?
DS: You know that there are two macro problems in our industry. One of them is finding and retaining patients in clinical trials (and it is very expensive to take this into account when developing a new drug). Therefore, at Parexel, we use a patient-centered approach for this. And in my role as CIO, I see the importance of empowering our teams with the best tools and technology, and the compelling opportunities that I call them digitized to streamline and improve the efficiency of the entire process.
An example would be investing in the use of real evidence, such as electronic medical records and electronic claims, or real data. This means using people’s social activity data to help us find patients. The second problem is finding places to conduct clinical trials, as participation in clinical trials requires patients to be referred somewhere to actually participate. So, we are looking at how to combine these two things with the help of technology.
TP: Good. So, Jonathan, what does all this technological innovation mean for patients and their communities?
DS: The work we do ultimately allows us to achieve the goal of providing a safe and effective therapy or treatment for them. We want to make it easier for patients to participate in clinical trials. We want to raise awareness and educate people that participating in clinical trials can help produce clinically relevant results that can reach patients faster, as we saw with pre-COVID therapy during the pandemic, right? So whether it’s orphan drugs, rare disease therapy, CNS therapy, or oncology, we want to use technology to bring these patients, researchers, and the work we do at CRO together so we can get these vaccines and treatments to market faster. .
TP: Well, Jonathan, thank you so much for the great conversation and all your ideas today.
DS: Todd, thank you, I really enjoyed it. This is a great way to convey the message that being in this industry is important for our health and the impact it has on our daily lives. Thank you very much.
TP: To find out more, click on the link below.
https://www.parexel.com